Basic Machine learning Methods (1) Dimension reduction
Workshop, Tsinghua University, Beijing, CN
In this workshop, I talked about the principles and applications of dimension reduction methods including PCA, tsne, Umap.
See the slides here
Talks and presentations
3D Genome Analysis Identifies Enhancer Hijacking Mechanism for High-Risk Factors in Human T-ALL
Talk, Tsinghua University, The 7th International Symposium on 3D Genomics, Beijing, CN
In this report, I talked about my own work exploring T-ALL 3D genome changes.
See the slides here
Having Fun in Hi-C Data Analysis
Report & Review, Zhu lab's Group Meeting, PUMC, CN
In this report, I reviewed Hi-C data analysis in almost all scales.
See the slides here
HiCDB: a sensitive and robust method for detecting contact domain boundaries
Talk, Huazhong Agricultural University, The 5th International Symposium on 3D Genomics , Wuhan, Hubei
In this report, I talked about my own method HiCDB to detect chromatin contact domain boundaries (CDBs) robustly and sensitively.
See the slides here See also the videos from www.seq.cn
Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation
Review, Michael lab's Group Meeting, Tsinghua, CN
In this report, I reviewed the data analysis in terminal differentiation based on promoter Hi-C and ChIP-Seq data which inspired me in the muscle differentiation data analysis.
See the slides here
From Structural Feature to Biological Functions
Review & Report, Michael lab's 12th Group Meeting, Tsinghua, CN
In this report, I reviewed the relationship between chromatin structure and biological functions and the preliminary results of HiCDB.
See the slides here
Inter-chromosomal interaction analysis based on population 3D genome modeling
Review, Michael lab's Group Meeting, Tsinghua, CN
In this report, I reviewed several 3D genome modeling technologies and a paper to analyze inter-chromosomal interactions.
See the slides here